Both are very good. LQ is next to Claytons where the action is plus fireworks right in front of hotel on Fridays and Saturdays nights at 9:15.
Both excellent choices,but yes the La Quinta has Clayton's next door and fireworks and live music on the Hilton Deck next door. Don't forget to try out the Taco's at Barry's Taco's and Margaritas right there on the Hilton beach front deck next to La Quinta. The La Quinta also has the World Birding and nature center and the sea turtle rescue center across the street.
Both hotels are beachfront and both have free breakfast.
Thank you for your replies and great feedback. I booked the La Quinta today. I decided on a partial ocean view room so that it's a little quieter. I've heard that it can get loud in the ocean view rooms with Clayton's next door and the pool down below. Thank you for your help.