Id look first at how long your stay is
I find it almost impossible to get out of Amsterdam even on a two week trip. Be stronger than I am :-)
The biggest issue most visitors face------where can I stay and how much is it going to cost me.
What are you most interested in seeing? Architecture? Windmills? Castles? Lakes?
In recent years our trips to The Netherlands have all been in November. In planning keep in mind weather will be the biggest determining factor. I can't think of too many things you would have to commit to before going. Plan multiple day trip itineraries and make up your mind after you get there.
A nice weather day will be bright sunshine with maybe just a little color left on the trees and about 55° (F). It can be beautiful.
To follow up on John's post he has been able to save folks an awful lot of money. If you haven't yet booked your lodging you can ask for help from him as well as others.
"Travel is fatal to prejudice, bigotry, and narrow-mindedness"--Mark Twain
Thanks to all who answered.
We will be there 10 days.
What things are you most interested in seeing? With 10 days there are plenty of ways to put your itinerary together just depends on particular interests in each place.