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6425 Transit Rd, Depew, NY 14043-1032
+1 716-684-4800
10:30 - 22:00
Closed now
See all hours
Sun - Sat 10:30 - 22:00
More Info
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23 Reviews from our TripAdvisor Community

Traveller rating
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Time of year
Showing 23: English reviews
Level Contributor
21 reviews
13 restaurant reviews
common_n_restaurant_reviews_1bd8 7 helpful votes
5 of 5 bubbles Reviewed 15 November 2016 via mobile

John and Mary's is a sub and chicken wing fast food restaurant. They have the best subs in the world. Their prices are reasonable. They have take out as well as plenty of seating inside. There are multiple locations around the western New York (Buffalo) area.

Thank Buffalo045
Jacksonville, Florida
Level Contributor
104 reviews
74 restaurant reviews
common_n_restaurant_reviews_1bd8 33 helpful votes
4 of 5 bubbles Reviewed 27 July 2016

Whenever I come back to the Buffalo area my first stop is John & Mary's for a "royal sub". Cappicola, Italian sausage, provolone cheese on a fresh sub roll. Great food at a good price.

Thank Mark W
Level Contributor
22 reviews
16 restaurant reviews
common_n_restaurant_reviews_1bd8 1 helpful vote
2 of 5 bubbles Reviewed 22 July 2016

I use to live in Buffalo and visit every couple of years. Usually go to the Harlem Rd. branch but the Pulaski Day Parade was going on So we went to the Transit RD, Store. SERVICE was both terrible and not friendly. I have been going to John & Marys since the mid fiftys. Need a new manager at this... More 

Thank Gary B
Lancaster, New York
Level Contributor
67 reviews
46 restaurant reviews
common_n_restaurant_reviews_1bd8 7 helpful votes
5 of 5 bubbles Reviewed 4 July 2016

This establishment is run by the Son of the original owner and meets the family tradition. Their hot (Cooked) subs are great. Their most famous is the Royal, sausage, cappicoli, salami lettuce and tomato w/ oil and/or mayo. The original John and Mary's on Harlem Road, where it all started was a high school hang out. That's where I had... More 

Thank OldFart565
Depew, New York
Level Contributor
10 reviews
8 restaurant reviews
common_n_restaurant_reviews_1bd8 4 helpful votes
2 of 5 bubbles Reviewed 25 February 2016

SUBS: John & Mary's original, back in the 1950's, was phenomenal. Even into the 60's and through the 90's it was great. I think the younger generation took over, and it's gone downhill (Lancaster location; don't know about the others). The sub rolls are still the best (I think), but they are sooo stingy with meats & cheese. This has... More 

Thank Deborah G
Buffalo, New York
Level Contributor
90 reviews
61 restaurant reviews
common_n_restaurant_reviews_1bd8 16 helpful votes
2 of 5 bubbles Reviewed 10 July 2015 via mobile

After having a great experience with dinner stopped here for some ice cream Had vanilla custard in a cone. The Ice cream tasted gritty And not creamy very disappointing. I eat a lot of custard. Talked to the only person I could inside and explained my issue The staff member , Not sure if she was management told me she... More 

Thank John S
Erie, Pennsylvania
Level Contributor
85 reviews
41 restaurant reviews
common_n_restaurant_reviews_1bd8 22 helpful votes
4 of 5 bubbles Reviewed 22 June 2015

They were kind enough to deliver to our hotel the pizza and boneless wings were good. The delivery was quick

Thank Alicia S
Depew, New York
Level Contributor
16 reviews
9 restaurant reviews
common_n_restaurant_reviews_1bd8 5 helpful votes
4 of 5 bubbles Reviewed 8 June 2015

Typical WNY sub place. Wether it is for subs, wings, from the fryer or ice cream (Seasonal) this long family owned business is a good choice for food. Pizza in my opinion is a little lackluster. Also from time to time anything with capicola can be a dicey. But overall a good place to eat otherwise.

Thank BingSeeker
Level Contributor
54 reviews
53 restaurant reviews
common_n_restaurant_reviews_1bd8 17 helpful votes
5 of 5 bubbles Reviewed 15 February 2015 via mobile

I've been going since I was a kid. To me, every time I return to buffalo I have to make a stop for a sub. Their subs are amazing, especially chicken finger. One bite and I am transported back to my childhood. You could ask me about the pizza and wings... But I've never had them. John & Mary's is... More 

Thank Bobzillaski
Level Contributor
142 reviews
70 restaurant reviews
common_n_restaurant_reviews_1bd8 97 helpful votes
2 of 5 bubbles Reviewed 11 December 2014

It was pizza special day $9.99 for a large one topping compared to $12.50. First thing my husband said upon trying it was it tasted like a frozen pizza. After we were done my daugter said even the fries were bad, not chrispy, not salty and soggy. We have lived in the neighborhood for 22 years and have not eaten... More 

1 Thank jpinj2

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Restaurant Details

Rating summary
  • Food
    3.5 of 5 bubbles
    4 of 5 bubbles
  • Value
    4 of 5 bubbles
    3.5 of 5 bubbles
Average prices
USD 12
American, Pizza, Fast food
Lunch, Dinner
Restaurant features
Takeout, Seating, Delivery
Good for
Cheap Eats, Child-friendly
Open Hours
10:30 - 22:00
10:30 - 22:00
10:30 - 22:00
10:30 - 22:00
10:30 - 22:00
10:30 - 22:00
10:30 - 22:00
Location and Contact Information
  • Address: 6425 Transit Rd, Depew, NY 14043-1032
  • Location: United States  >  New York (NY)  >  Depew
  • Phone Number: +1 716-684-4800

Questions & Answers

Questions? Get answers from John & Marys staff and past visitors.
Posting guidelines
Typical questions asked:
  • Do you have gluten-free options?
  • Is there a dress code?
  • Do you allow dogs on the outdoor patio?