Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Dozens of nightclubs, hundreds of restaurants and some of Mexico's best beaches await you in Puerto Vallarta. The original colonial town still shines through an endless selection of shopping, art galleries, water and land activities, and hotels. Walk the malecon (boardwalk) and just try to take it all in.

Wild horses can actually drag you away…to Chincoteague Island. Here, ponies run wild, you can catch or dig up your own seafood, and the beaches bring literal breaths of fresh air. The Chincoteague National Wildlife Refuge is a wonderfully unspoiled spot for bird watching, horseback riding, swimming and biking. Every summer since 1925, all of the feral ponies on Assateague are rounded up for the world-famous annual Pony Swim over to Chincoteague.

U.S. citizens still need to jump through a few hoops to visit Cuba, but as visitors from around the world know, this island offers some amazing opportunities for cultural exchange. Havana is a mix of old-world architecture and of-the-moment culture. Head out of the capital city to the small town of Trinidad to see more Spanish colonial architecture. It’s a UNESCO World Heritage Site and a fantastic home base for a visit to the Valley of the Sugar Mills, a pocket of land that formerly served as the centre of Cuba’s sugar industry.

With its sandy North Shore beaches, rocky outcrops, green parks, hemlock woods and wild estuaries full of shorebirds, it is no wonder that Gloucester has attracted such a rich and diverse artists' community. Fitz Hugh Lane, Winslow Homer and John Sloan are just some of the artists who have taken inspiration from Gloucester's beautiful surrounds. Still boasting dozens of galleries and boutiques, as well as museums, theaters and an artists' colony, the city's art scene clearly continues to thrive.

Saint John, New Brunswick, is the only city on the shore of the Bay of Fundy, home to the world’s highest tides. Canada’s oldest incorporated city, Saint John is a popular tourist destination known for its historic uptown streetscapes, cultural attractions and natural wonders. Popular sights include the Reversing Rapids, where the Bay collides with the St. John River, the City Market with local vendors and artisans, the New Brunswick Museum and the trails and beauty of Rockwood Park.