Old-world villages and story-book chateaux bedeck the Loire, once fought over by Gauls, Romans, Visigoths and even Attila the Hun. Hire bikes and roll through the lush valley, visiting fortresses in Amboise and Angers, UNESCO-designated Chartres Cathedral and the Gothic cathedral in Nantes. The Musée Jules Verne houses replicas of futuristic inventions designed by the author. Pay respects to other former residents: the Romans in Tours, the cave dwellers of Touraine, and the liberator of Orleans, Joan of Arc.

From Shoreditch’s swaggering style to Camden’s punky vibe and chic Portobello Road, London is many worlds in one. The city’s energy means that no two days are the same. Explore royal or historic sites, tick off landmarks from your bucket list, eat and drink in exclusive Michelin-starred restaurants, enjoy a pint in a traditional pub, or get lost down winding cobbled streets and see what you stumble across – when it comes to London, the possibilities are endless.

Located in northwest Italy’s Lombardy region, the province of Bergamo offers more than just a day-trip diversion from the big city of Milan. This hilltop town is known for its architectural gems, including medieval and Renaissance structures that continue to amaze tourists and locals alike. Don’t miss the historic Piazza Vecchia with its 12th and 16th century buildings. And Bergamo’s Galleria dell’Accademia Carrara is an art gallery featuring works from Italian legends including Botticelli, Titian, Canaletto and Raphael, to name a few.

One of the most popular regions in Italy, Tuscany stretches from the Tyrrhenian Sea to the Apennines. Its main cities include Florence, Pisa, Siena, Lucca, Arezzo and Livorno. Drive between stunning sites like Florence's cathedral and Uffizi Gallery and the Leaning Tower of Pisa. Or join a bike tour and pedal past sun-baked olive groves and vineyards. Don't miss the towers of San Gimignano or serene northern hill towns. For a more modern take, hit one of Florence's hip clubs, such as Space Electronic.

This Tuscan hill town will transport you back to the Middle Ages. Siena's grand cathedral, built in the 1200s, has treasured artworks and marvellous marble floors. The Piazza del Campo, the main town square, is a UNESCO World Heritage Site. It's also home to the Palio, perhaps the most infamous horserace in the world. No goofy hats and mint juleps here—this is a mediaeval tradition involving bareback riders racing on cobblestones (so as you might imagine, it's quite dangerous). Siena is an easy daytrip by train from Florence, just 43 miles away.

Catania has been a prize of many empires over the centuries, from Greeks to Romans to Arabs to Normans to Spaniards (to name a few). But its citizens have a more dangerous enemy right in their backyard—Mount Etna, Europe's largest and most active volcano, which destroyed the city with earthquakes and lava flows in 1693. Look closely at the baroque buildings dating from after the eruption—you'll notice a creative use of lava.

Lying in south central Turkey, the moonscaped region of Cappadocia, southeast of Ankara, is most famous for unique geological features called fairy chimneys. The large, cone-like formations were created over time by erosion of the relatively soft volcanic ash around them. Past cultures have dug into them to create dwellings, castles (like Uchisar) and even entire underground cities like Kaymakli and Derinkuyu, used as hiding places by early Christians. Nearby Kayseri is the gateway to the area.

Dubai is a destination that mixes modern culture with history, adventure with world-class shopping and entertainment. Catch a show at the Dubai Opera, see downtown from atop the Burj Khalifa and spend an afternoon along Dubai Creek exploring the gold, textile and spice souks. If you’re looking for thrills, you can float above the desert dunes in a hot air balloon, climb aboard a high-speed ride at IMG Worlds of Adventure or skydive over the Palm Jumeirah.

Lively Antigua and Barbuda move to the music of steel drums. You can visit a different beach each day and not repeat yourself for a full year—and that's why tourists and celebrities alike flock to this sun-soaked Caribbean island. Take a day cruise, rent some diving gear or cruise up the beach on a Segway for a real adventure, island-style.