Just a few miles west of Naples (and easily reached by train), the ancient seaside city of Pozzuoli is probably best known for its bradyseism, a raising and lowering of the Earth’s surface due to underground volcanic activity. Many sites remain from Pozzuoli’s days as an important Roman port, including the Macellum or Temple of Serapis, which for many years was submerged under water. The Flavian Amphitheater (Italy’s third-largest) and the Cathedral of Rione Terra are other popular attractions.

Stretching along the southern side of Italy's Sorrentine Peninsula, the Amalfi coast dazzles with its mysterious grottos, craggy cliffs and shimmering bays. Grab a seat on the sea side of a regional bus to soak up views on the fabled route from artsy Positano to Amalfi. Ravello offers some respite from the crowds, plus the stunning Villa Cimbrone, which overlooks the Bay of Salerno. The winding streets of Sorrento's historic district are filled with craftspeople. Capri is only a hydrofoil or ferry ride away.

Three miles of twisty mountain roads up from Amalfi, the gorgeous resort of Ravello has been attracting celebrities for centuries, including Richard Wagner, Greta Garbo, Gore Vidal and D.H. Lawrence, who wrote Lady Chatterley’s Lover here. Ravello’s Duomo (Cathedral) and Villa Cimbrone (both 11th century) and Villa Rufolo (13th century) are all magnificent sights. The annual summer Ravello Festival began as a salute to Wagner’s music, but now showcases a wide range of music and arts.

The region of Campania curves around the bays of Naples and Sorrento, with towering Vesuvius and mountain ranges and massifs looming above. Ancient classical ruins are scattered throughout the region, from the ruins of Pompeii and Herculaneum to the Greek temples in Paestum. Popular resort towns include charming Sorrento and Amalfi, upscale Positano and haven for the elite, Ravello. For even more memorable sights, catch a ferry from Sorrento or Naples to the isle of Capri, home of the magical Blue Grotto.

Catania has been a prize of many empires over the centuries, from Greeks to Romans to Arabs to Normans to Spaniards (to name a few). But its citizens have a more dangerous enemy right in their backyard—Mount Etna, Europe's largest and most active volcano, which destroyed the city with earthquakes and lava flows in 1693. Look closely at the baroque buildings dating from after the eruption—you'll notice a creative use of lava.

Imerovigli looks exactly as a Santorini village should: iconic whitewashed buildings with sapphire domes, narrow crisscrossing walking paths, epic sunsets. Set sail on a guided boat tour of nearby volcanic features or spend the day exploring the remains of Skaros, a 13th-century Venetian palace. Cap it all off with a simple but decadent meal of local delicacies.