Stroll Las Ramblas and enjoy Barcelona's unique blend of Catalan culture, distinctive architecture, lively nightlife and trendy, stylish hotels. You'll find Europe's best-preserved Gothic Quarter here, as well as amazing architectural works by Gaudi. La Sagrada Familia, considered Gaudi's masterpiece, is still under construction (your entrance fee helps to fund the project). Feel like a picnic? Look no further than the rambunctious La Boqueria market, where you can stock up on local delicacies.

It’s nicknamed the Eternal City for a reason. In Rome, you can drink from a street fountain fed by an ancient aqueduct. Or see the same profile on a statue in the Capitoline Museum and the guy making your cappuccino. (Which, of course, you know never to order after 11 am.) Rome is also a city of contrasts—what other place on earth could be home to both the Vatican and La Dolce Vita?

Nestled along the east coast of the Isle of Man, the small holiday resort of Douglas oozes charm. Visitors may enjoy horse-drawn tram rides along its pedestrian shopping promenade, dotted with restored 19th century buildings and lining the shore with independent boutiques and High Street shops. The new Villa Marina and Gaiety Theatre Complex entertain with all sorts of performing arts and films, while the gardens and museums sprinkled throughout the town promise relaxation and culture.

A city with a 200-year Southern heritage, visitors will find activities that celebrate Huntsville’s rich history, as well as attractions that highlight the city’s scientific side. At the Alabama Constitution Village, villagers in period clothing take time from their daily chores to guide you through eight reconstructed Federal style buildings. Younger visitors will love the 150 hands-on activities at the Sci-Quest Hands-on Science Centre and older children will learn what it takes to be an astronaut at the U.S. Space and Rocket Centre. Looking for outings with a cultural flair? Landmarks such as the Huntsville Botanical Garden and Huntsville Museum of Art are must sees.