Home to Windsor Castle, the second residence of Queen Elizabeth II, Windsor is a popular day-trip destination from London. Those who tarry in the riverside town fill their time wandering the cobbled streets, popping in and out of the luxe boutiques, restaurants, and tea shops that tumble down toward the Thames River.

Just west of London, Reading offers redbrick Victorian buildings, medieval ruins, a thriving university, and pretty waterside walks along the Thames River. Its student community and annual rock-music blowout—the Reading Festival—add an offbeat edge.

In the "city of dreaming spires", academia takes centre stage. Gaze out at Oxford's world-famous colleges from the top of St Mary's Church tower before heading into the city's pedestrian-friendly streets. The University's Botanic Garden and Ashmolean Museum are Britain's oldest. Follow your nose to the Covered Market for the makings of a picnic to enjoy on a punt or in the University Parks. Mix the historic and modern with visits to the 12th- century village church of Iffley and trendy Cowley's ethnic shops and music venues.

Boasting a historical dockyard housing Henry VIII’s Mary Rose and Lord Nelson’s HMS Victory, Portsmouth has maritime heritage written all over it. Museums aside, the city still lives and breathes the sea—best exemplified in its nautical spirit, cobbled historic district, and sail-shaped Spinnaker Tower viewpoint.

Southwest of London is Southampton (Soton to the locals), a metropolitan area centered around the port. However, tucked away on the side streets are ancient gems such as the Tudor House, Mottisfont Abbey, and "God's House," a museum located in a tower in the medieval wall. The ultra-modern Sea City Museum celebrates Southampton's seafaring past and the RMS Titanic. Looking for nightlife? Travelers can dance the hours away with bars, clubs, and live music, all accessible by public transportation.

Everyone who visits Paris for the first time probably has the same punchlist of major attractions to hit: The Louvre, Notre Dame, The Eiffel Tower, etc. Just make sure you leave some time to wander the city’s grand boulevards and eat in as many cafes, bistros and brasseries as possible. And don’t forget the shopping—whether your tastes run to Louis Vuitton or Les Puces (the flea market), you can find it here.

Amsterdam is truly a biker’s city, although pedaling along the labyrinthine streets can get a little chaotic. Stick to walking and you won’t be disappointed. The gentle canals make a perfect backdrop for exploring the Jordaan and Rembrandtplein square. Pop into the Red Light District if you must—if only so you can say you’ve been there. The Anne Frank House is one of the most moving experiences a traveller can have, and the Van Gogh Museum boasts a sensational collection of works.

Edinburgh is Scotland’s capital city, renowned for its heritage, culture and festivals. Take a long walk around the centre to explore the World Heritage Sites of the Old Town and New Town, as well as all the area’s museums and galleries. Then stop for a delicious meal made from fresh Scottish produce before heading out to take in one of Edinburgh’s many events — including the famous summer festivals of culture, or the Winter Festivals of music, light and ceilidhs.

Munich was almost completely destroyed in two world wars, yet it's managed to recreate much of its folkloric, Bavarian past. Oktoberfest is legendary, but you can visit the Hofbrauhaus any time of year for an immense beer. Olympiapark, the site of the 1972 games, is not to be missed (you can skate on the Olympic ice rink and swim in the pool). On a somber note, take time to visit the concentration camp at Dachau—it's an intense, yet unforgettable, glimpse into the not-too-distant horrors of the Holocaust.

Nice has a cosmpolitan Riviera vibe, and you'll enjoy exploring its fashionable boutiques and restaurants and sunning yourself on its popular beaches. (Just don't expect soft sand—these beaches have pebbles.) Walk up to Castle Hill for a beautiful view of the city, the Bay of Angels and of course, the bright blue water that gave the Cote d'Azur its name.

Stroll Las Ramblas and enjoy Barcelona's unique blend of Catalan culture, distinctive architecture, lively nightlife and trendy, stylish hotels. You'll find Europe's best-preserved Gothic Quarter here, as well as amazing architectural works by Gaudi. La Sagrada Familia, considered Gaudi's masterpiece, is still under construction (your entrance fee helps to fund the project). Feel like a picnic? Look no further than the rambunctious La Boqueria market, where you can stock up on local delicacies.

It’s nicknamed the Eternal City for a reason. In Rome, you can drink from a street fountain fed by an ancient aqueduct. Or see the same profile on a statue in the Capitoline Museum and the guy making your cappuccino. (Which, of course, you know never to order after 11 am.) Rome is also a city of contrasts—what other place on earth could be home to both the Vatican and La Dolce Vita?

Dubai is a destination that mixes modern culture with history, adventure with world-class shopping and entertainment. Catch a show at the Dubai Opera, see downtown from atop the Burj Khalifa and spend an afternoon along Dubai Creek exploring the gold, textile and spice souks. If you’re looking for thrills, you can float above the desert dunes in a hot air balloon, climb aboard a high-speed ride at IMG Worlds of Adventure or skydive over the Palm Jumeirah.

The first time you go to New York, go ahead and be a sight-seer—everyone should visit the Statue of Liberty, the Met, Times Square, etc. But on a return trip, pick a neighbourhood and go deep. You’ll find hole-in-the-wall bars, great delis, quirky shops… exploring the non-touristy side of New York is an incredibly rewarding experience for a traveller.

From the Magic Kingdom to magical spa treatments, Orlando sparkles with the promise of adventure. Spend a day exploring the world-famous Disney theme parks or screaming your head off on a Universal Studios roller coaster. For a less adrenaline-pumping afternoon, enjoy the quiet natural beauty of the Harry P. Leu Gardens or enjoy a seaweed scrub at a luxury day spa. Savor fresh and local ingredients at one of Orlando’s James Beard-nominated restaurants.