Home to nearly nine million and powering an economy that exceeds both Hong Kong's and Thailand's, Osaka packs quite a punch. The confident, stylish city is a shopping hub, with fabulous restaurants and nightlife. It's an ideal base for exploring the Kansai region: Kyoto's World Heritage Sites, Nara's temple and Koya-san's eerie graves are within 90 minutes by train. Top city attractions include the aquarium, Osaka Castle, Universal Studios Japan and the futuristic Floating Garden Observatory.

Famous for its luscious beef and crisp, pure sake, the Japanese port of Kobe is a thriving metropolitan city with an international feel. The sake-brewing season runs from October through April, and that's the best time to take a tour of a kura (the Japanese word for brewery). Visit the Hakutsure Sake Brewery Museum year-round. Naturally, the nightlife here is prime perfection.

Commerce keeps Nagoya’s downtown popping with life, but there’s more than just manufacturing to this industrial powerhouse. Nagoyans meet for plates of crisp-friend miso katsu; make weekend trips to nearby Shinto shrines; and count down the days to the city’s autumn Nagoya Festival.

As the social hub of one of the world’s largest metropolises, Shibuya promises to please. Along Japan’s shops housed in skyscrapers and trademark neon signs, hordes of shoppers cross the iconic intersection every minute in a demonstration of the organised chaos that epitomizes Tokyo.

Tradition collides with pop culture in Tokyo, where you can reverently wander ancient temples before rocking out at a karaoke bar. Wake up before the sun to catch the lively fish auction at the Toyosu Market, then refresh with a walk beneath the cherry blossom trees that line the Sumida River. Spend some time in the beautiful East Gardens of the Imperial Palace, then brush up on your Japanese history at the Edo-Tokyo Museum. Don’t forget to eat as much sushi, udon noodles, and wagashi (Japanese sweets) as your belly can handle.

Probably best known for its eponymous beer, Sapporo—the capital of Hokkaido, Japan’s northernmost island—has maintained the youthful and open atmosphere of the 1972 Olympic Winter Games, drawing international visitors for its annual Snow Festival and its world-famous ramen. Those seeking out the full diversity of Japanese cuisine will want to visit: a city with a ramen-inspired theme park is one that embraces and pampers foodies.

Hong Kong's a great city for an adventurous eater. Stop at a street vendor for fish balls on a stick or stinky tofu. Bakeries offer wife cake, pineapple buns and egg tarts. Or opt for as much dim sum as you can eat. If you're tired of local and regional Chinese specialties, check out upscale offerings from some of the world's top chefs, like Joel Robouchon and Alain Ducasse.

Perched in a high mountain valley, Huanglong or Yellow Dragon National Park offers invigorating adventure options. The ambitious can trek to Lhasa, whitewater raft or embark on multi-day river journeys. Alternatively, a five-mile trot brings you to five terraced, temple pools glowing with stunning hues.

Bangkok is full of exquisitely decorated Buddhist temples—as you go from one to the next you’ll be continually blown away by the craftsmanship and elabourate details. But if you’d rather seek enlightenment in a gourmet meal, or dance the night away, you’ll also enjoy Bangkok—the restaurant and nightclub scenes here are among the best in the world.

Singapore is known as a bustling metropolis that also happens to be one of the cleanest and safest cities of its size in the world. (Just make sure you heed the local laws—something like spitting in the street might merely be considered rude in your hometown, but here, it carries a severe penalty.) You'll find historic sites like the Thian Hock Keng temple, superlative shopping (including gargantuan malls) and numerous beaches.

Bali is a living postcard, an Indonesian paradise that feels like a fantasy. Soak up the sun on a stretch of fine white sand, or commune with the tropical creatures as you dive along coral ridges or the colorful wreck of a WWII war ship. On shore, the lush jungle shelters stone temples and mischievous monkeys. The “artistic capital” of Ubud is the perfect place to see a cultural dance performance, take a batik or silver-smithing workshop, or invigorate your mind and body in a yoga class.

Cairns is the perfect city for merry revelers, passionate divers and adrenaline junkies, offering booming nightlife and heart-pounding adventure amid a vibrant, tropical setting.  This friendly Queensland city of 130,000 is a gateway to the Great Barrier Reef, Daintree National Park, Cape Tribulation, Cooktown and the rest of Cape York Peninsula. Embark on an eco-adventure or take a dip in a lagoon pool before hitting the town to unwind and shake what you’ve got Down Under.