Once a thriving steel town, Youngstown suffered an economic decline immortalized in song by Bruce Springsteen. However, the innovative city has made a comeback, spawning a surge in industry, from software to food to the arts. Dozens of galleries, museums, performance venues and historic sites celebrate the culture of the area. Miles of hiking trails and green spaces offer energetic activities to active travelers. Sports are also highly valued, Youngstown being home to a host of pro athletes.

You're on island time the moment you set foot in Jamaica. Ocho Rios, a port of call for many cruise lines, also boasts some of the most luxe resorts and spas in the Caribbean. And once you've had your stresses melted away in the island sun, you can head out for a night of dancing and reggae music.