It's no wonder Machu Picchu is Peru's most-visited site. Dating to the mid-1400s, it's a marvel of mortar-free limestone architecture perched on a high plateau deep in the Amazonian jungle. Get there via train from Cusco or, if you're not faint-hearted, make the trip on foot via a multi-day hiking trail—you'll travel through deep Andean gullies and enjoy stunning views.

Peru’s Aguas Calientes offers weary travellers the chance to soak in thermal baths and browse for artisan souvenirs before (or after) using the town as a gateway to Machu Picchu. Its remote location deep in the Urubamba Valley is accessible to tourists only by train.

Is there a better way to cap off a day of pristine reef diving and heart-pumping adventure sports than by sipping a sunset cocktail? Didn’t think so! From ziplining to deep sea fishing to exploring the military-protected archipelago of Cayos Cochinos, the Honduran island of Roatan is a playground for lovers of water sports and ecotourism. Landlubbers will flip for the Carambola Botanical Gardens, a tour of the Stone Castle Cameo Factory or exploring the beaches on horseback.

Home to the Phoenix metropolitan area and its more than 3.4 million residents, Central Arizona offers an amazing array of museums, cultural venues and outdoor adventures. The Valley of the Sun boasts hopping nightlife and a thrilling selection of restaurants, resorts and spas. Discover Old West and Native American history. Hike among the cacti in the Sonoran desert. Try your hand at ranching in Glendale. Drive the Superstition Mountains. Visit Frank Lloyd Wright's Taliesin West in Scottsdale.