Sizzling thermal waters flow from volcano-heated springs in remote, rugged Patagonia. It’s the ideal spa destination for those who want some eco-adventure when they emerge from the therapeutic waters. The most decadent spa address is Puyuhuapi, in the north of the region, accessible only by boat.

The largest island along Brazil's coast and, literally, a “beautiful island,” Ilhabela offers visitors almost 40 kilometres of pristine beaches and a tropical island's worth of hiking trails, waterfalls and even a nascent party scene. At 207 kilometres from the city of São Paulo, Ilhabela can get crowded, so try to get your beach time in during the work week.

With a rich pre-Colombian history, Ecuador's capital was founded on the ruins of an Incan city but offers everything a modern traveller might need. It remains the least-altered historic centre in Latin America and has been designated a UNESCO World Heritage Site. Quito’s important sites include baroque gems like San Francisco and Santo Domingo monasteries, as well as La Compañía church and college. This huge city sprawls across a breathtaking Andean valley surrounded by volcanic peaks.

Charleston is known for great food (you won’t find better grits on the planet) and colourful history. But why do travellers return year after year? We’ll blame the genuine Southern hospitality this city extends to each and every visitor.