The largest game reserve in South Africa, Kruger National Park is basically a synonym for the word "safari." Home to over 500 bird species, 100 reptiles, nearly 150 mammals, multiple archaeological sites, and a stunningly diversity of trees and flowers, Kruger is the country’s flagship national park. Adventurers can explore the park in a 4x4, take a bush walk or fly above in a hot-air balloon.

Perched on Sri Lanka’s southwest coast, Galle wears its history on its sleeve. Windswept beaches and nodding palms surround its colonial-era showpiece, a 16th-century Portuguese-built fort, while the rest of the city is trimmed with Dutch-style houses, quirky shops, whitewashed mansions, and heritage museums.

Belek, a resort town on the Turkish Riviera, is known for very clean, white-sand beaches surrounded by pine forests. History buffs should plan day trips to the Roman ruins at Perge and the Aspendos amphitheater. Or if you’d prefer a round of golf, bring your clubs—there are excellent courses in the area.

A large island, approximately 20 by 20 kilometres, Djerba lies just off the northeastern coast of Africa, in southeastern Tunisia, near the Libyan border. Set on the Gulf of Gabes, the island is known for an eclectic population of residents and tourists, splendid beaches and picturesque villages that feature distinctive, square, whitewashed houses. Houmt Souq is the one large town, with bustling markets and lively outdoor cafes. Djerba, which offers a pirate's castle and fortress-like mosques, is believed to have been the inspiration for Homer's Odyssey. Accessible from the south of Tunisia, a road originally built by the Romans connects the island to the mainland.

Once known for smog, traffic and tacky architecture, Athens is a city reformed thanks to fortunes brought by the 2004 Summer Olympics. Spotless parks and streets, an ultra-modern metro, new motorways, an accessible airport and all signs in perfect English make the city easily negotiable. Meriting more than a stopover en route to the islands, sophisticated Athens sites include many pillars of Western history, from the Acropolis to the Temple of Olympian Zeus, as well as treasures in the National Archaeological Museum.

Lying in south central Turkey, the moonscaped region of Cappadocia, southeast of Ankara, is most famous for unique geological features called fairy chimneys. The large, cone-like formations were created over time by erosion of the relatively soft volcanic ash around them. Past cultures have dug into them to create dwellings, castles (like Uchisar) and even entire underground cities like Kaymakli and Derinkuyu, used as hiding places by early Christians. Nearby Kayseri is the gateway to the area.

It’s nicknamed the Eternal City for a reason. In Rome, you can drink from a street fountain fed by an ancient aqueduct. Or see the same profile on a statue in the Capitoline Museum and the guy making your cappuccino. (Which, of course, you know never to order after 11 am.) Rome is also a city of contrasts—what other place on earth could be home to both the Vatican and La Dolce Vita?