Colorful Phuket is a mélange of lifestyles, a place where tranquil monks navigate the same streets as pumped up nightclubbers. The ornate temples and lively cafes of Old Town are prime spots for exploration. Check out the Shrine of the Serene Light and the aromatic Nguan Choon Tong herb shop. Browse and bargain for pretty trinkets at the nearby Thai Amulet Market. Don’t miss an opportunity to take in a performance at the epic Siam Niramit Phuket theater, a true cultural extravaganza.

Phuket offers a rainbow spectrum of spectacular holiday sights from blue lagoons and pink sunsets to orange-robed monks. Three wheeled-Tuk Tuks, taxis, buses and long tailed boats transport visitors between these marvels. Phuket's south coast offers its most popular beaches. The north is more tranquil. Koh Phi Phi, Phang Nga Bay and Patong Beach are popular spots. Diving, snorkeling, wind surfing and sailing are just a few active options. Inland, forested hills, mountains and cliffs wait to be explored.

The cultural hub of Malaysia, Kuala Lumpur is visually defined by the iconic Petronas Twin Towers, which, at 88 stories high, are the tallest twin buildings in the world and a vision of modern architecture. On the flip side, the Sri Mahamariamman is the oldest Hindu temple in Malaysia, its façade a colorful totem pole of iconography. Shopping at the Central Market is a joyful experience that involves haggling, handicrafts, and happiness.

Bangkok is full of exquisitely decorated Buddhist temples—as you go from one to the next you’ll be continually blown away by the craftsmanship and elabourate details. But if you’d rather seek enlightenment in a gourmet meal, or dance the night away, you’ll also enjoy Bangkok—the restaurant and nightclub scenes here are among the best in the world.

Vietnam's bustling largest city sets the cultural and economic pace for the country. The former Saigon boasts charming French colonial architecture and wide boulevards, usually thronged and choked with traffic. Taxis are an option for seeing the sprawling city. The War Remnants Museum shows the Vietnam War through Vietnamese eyes. Don't miss the impressive Jade Emperor Pagoda. Go to the frenetic Ben Thanh Market for food, flowers or frogs. Tour through the Mekong Delta, past rice paddies and houseboats.

Singapore is known as a bustling metropolis that also happens to be one of the cleanest and safest cities of its size in the world. (Just make sure you heed the local laws—something like spitting in the street might merely be considered rude in your hometown, but here, it carries a severe penalty.) You'll find historic sites like the Thian Hock Keng temple, superlative shopping (including gargantuan malls) and numerous beaches.

Chaotic, crowded, and cosmopolitan, Jakarta, the capital of Indonesia, is a city of contrasts. Home to millions of people from around the world, the city is a mixture of languages and cultures, poverty and wealth. The city boasts some of the best nightlife in Asia and some of the worst traffic. Every holiday, the locals escape the pollution and the crowds to enjoy relaxing diversions like Ancol Dreamland, an amusement area featuring water parks, beaches, golf courses, and a SeaWorld.

Hong Kong's a great city for an adventurous eater. Stop at a street vendor for fish balls on a stick or stinky tofu. Bakeries offer wife cake, pineapple buns and egg tarts. Or opt for as much dim sum as you can eat. If you're tired of local and regional Chinese specialties, check out upscale offerings from some of the world's top chefs, like Joel Robouchon and Alain Ducasse.

Shanghai is the cool, confident face of modern China, and its energy is infectious. Go to the Bund to watch ships on the river and marvel at the huge variety of architectural styles on display, or watch the crowds go by in People’s Square. Shoppers should make a beeline for the Fabric Market, where you can have a suit or dress tailor-made for you at bargain prices. At night, explore all manner of fashionable restaurants, bars and nightclubs or just stroll through the city enjoying the spectacular neon lights.

Tradition collides with pop culture in Tokyo, where you can reverently wander ancient temples before rocking out at a karaoke bar. Wake up before the sun to catch the lively fish auction at the Toyosu Market, then refresh with a walk beneath the cherry blossom trees that line the Sumida River. Spend some time in the beautiful East Gardens of the Imperial Palace, then brush up on your Japanese history at the Edo-Tokyo Museum. Don’t forget to eat as much sushi, udon noodles, and wagashi (Japanese sweets) as your belly can handle.

Lovely, laid-back Melbourne has something for everyone: family fare, local and international art, haute boutiques, multicultural dining, Australian and Aboriginal history, spectator sports, and pulsing, swanky nightlife. Cruise on the free City Circle Tram loop to check out unique attractions like the Royal Botanical Gardens and the Healesville Sanctuary, which buzzes with local animal species.

City slickers, culture vultures and beach bums alike fall in love with Sydney. Hang ten at famed Bondi Beach or stroll the calmer sands of Coogee.  Cash burning a hole in your pocket? You’ll find great shopping in the Rocks district and along George and Pitt Streets. Climb to the top of the Harbour Bridge or take a skywalk on Sydney Tower for a 360-degree view of the city. But whatever you do, don’t leave town without cuddling the koalas in the Taronga Park Zoo—they’re ridiculously adorable.