Definitely worth the visit, especially if you're in the Cannaregio area. The collection has a fine group of Venetian Renaissance and Baroque artists -- Bernini, Guardi, Mantegna, Tintoretto, Titian, Vivarini and much more. Plus a group of Dutch Golden Age paintings from Steen, Van Ostaade, van de Velde and others. If you're near the Rialto on the San Polo side of the Grand Canal, you can take a traghetto gondola across the Canal for two euros a person. Catch the traghetto at Rialto and you're just a few steps from the Ca' d'Oro entrance.