From the U.S. State Department:
Millions of U.S. citizens safely visit Mexico each year for study, tourism, and business, including more than 150,000 who cross the border every day. The Mexican government makes a considerable effort to protect U.S. citizens and other visitors to major tourist destinations, and there is no evidence that Transnational Criminal Organizations (TCOs) have targeted U.S. visitors and residents based on their nationality. Resort areas and tourist destinations in Mexico generally do not see the levels of drug-related violence and crime reported in the border region and in areas along major trafficking routes.
Nevertheless, U.S. travelers should be aware that the Mexican government has been engaged in an extensive effort to counter TCOs which engage in narcotics trafficking and other unlawful activities throughout Mexico. The TCOs themselves are engaged in a violent struggle to control drug trafficking routes and other criminal activity. As a result, crime and violence are serious problems throughout the country and can occur anywhere. U.S. citizens have fallen victim to TCO activity, including homicide, gun battles, kidnapping, carjacking and highway robbery.
You should defer non-essential travel to the state of Chihuahua. The situation in the state of Chihuahua, specifically Ciudad Juarez, is of special concern. Ciudad Juarez has one of the highest murder rates in Mexico. The Mexican government reports that more than 3,100 people were killed in Ciudad Juarez in 2010 and 1,933 were killed in 2011. Three persons associated with the Consulate General were murdered in March 2010. The state of Chihuahua is normally entered through Columbus, NM, and the El Paso, Fabens and Fort Hancock, TX, ports-of-entry. There have been incidents of narcotics-related violence in the vicinity of the Copper Canyon in Chihuahua.
U.S. State Department Warning