The hotel is what you should expect from Four Seasons. The addition of the Sports Club LA is a real treat. Being able to grab a workout while on the road in such luxury and with such ease is so rare. My favorite hotel now in SF.

My husband and I stayed 3 nights at the Four Seasons San Francisco in early January 2012.
The position of the hotel is very centrally located and you can walk to most places even down to Fishermans Wharf. The room was very large and roomy as per usual in a Four Seasons Hotel and the window seat was wonderful for sitting and watching the world on the street below.
The Four Seasons never fails in its level of cleanliness. The rooms were immaculately clean and the hotels themselves always have the most beautiful aroma in the hallways and public areas. I have to make mention of Karen at the Concierges desk. She was absolutely marvellous helping us arrange our hire car and even managed to have the car delivered to the hotel for us. She was very helpful and made this part of our trip a lot easier. Thankyou very much Karen. All the staff at the hotel could not have been nicer.

Location is excellent for SFMOMA & other museums, Union Sq shopping and restaurants, financial district. Room and service are fine as you'd expect. A little annoying: 2-elevator-trip to get in and out of the building; advertised courtesy car- starts at 5pm, there is only one, first-come-first-served, expect to take cabs. Really annoying at all Four Seasons: $15/day for Internet access when it is free at many inexpensive and moderately-priced hotels and it is not even available in lobbies. Breakfast at Seasons is reasonably expensive and very nice. Sun & Mon $20-burger-&-wine-or-beer is a good deal.
Good alternatives: Mandarin (after their renovation is complete in Spr 2012) for gorgeous views; Ritz Carlton if you don't mind being on Nob Hill.

We stayed for a week for a medical convention in one of the Superior suites. They made us feel very welcome and had nice welcome amenities for our two kids. They graciously gave us a microwave and small fridge so we could have food for the children, and they also provided us with yoga mats to use in our room as well. No other place has met all of our requests before.
Beds were comfortable, room service was great, valet was very helpful and provided us a town car to the airport.
Shopping is close by, so are good restaurants. The restaurants in the hotel are very good too. Will definately stay here again.