What a great drive along the bluffs. We drove at dusk, incredible sky to go along with the river and bluffs. Take your time and enjoy the views! More

The trip for Lake City to LaCrescent, Mn is premier. Take your time and take lots of pictures More

Slowly but surely this hiway is being repaired. It is pretty good now, but for years it felt like you were traveling in a lumber wagon while in your lexus. More

Non-stop gorgous vista's of the Missippi River with quaint river towns along the way. Lots to see and do. Especially breath-taking in the fall when the hardwood forests are at their peak color or during bird migration times (including tundra swans). More

Maybe I'm spoiled; I've driven this road a bazillion times. I've lived in La Crosse most of my life. More

Gorgeous drive. I highly recommend traveling the Great River Road Scenic By-way from the Twin Cities to the Quad Cities. One of the most beautiful sections of road in the country. More

This route is beautiful year 'round. Spring: Mississippi Flyway - best time to check out the bird migration heading north. Summer: The sailboats on Lake Pepin - check out Hok-Si-La Park on the waterfront. Late Winter: Bald eagles - too awesome for words! More

I have to agree if your talking about winona and hwy 61, it does not compare to the best highways in the US, however you start from duluth and are driving the north shore drive part of 61, then your talking something really special. Indeed, Ive actually read where its the 2nd most beautiful highway in the world, (not just... More

I can't agree with the comment that it's one of the most beautiful drives in America, I can think of a dozen better very quickly. However for the area it's nice. More